Only as advised by your healthcare professional. Always tell your doctor or pharmacist about all medicines you take, including medicines purchased at pharmacies and supermarkets and natural products.
COPD Management
A flare-up (exacerbation) is when symptoms suddenly get worse. Early treatment can help reduce the risk of lasting lung damage.1
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Your plan may include staying up to date with vaccinations, taking your medicines as prescribed, stopping smoking, and avoiding triggers (like colds, smoke, or dusty environments). Ask your healthcare professional for a personalised plan.
About BREZTRI
BREZTRI is a prescription medicine used long term to treat chronic obstructive pulmonary disease (COPD). When used regularly, BREZTRI helps to make breathing easier and also helps to prevent flare-ups of symptoms (exacerbations).
BREZTRI is a combination of 3 medicines in one device that work together to improve your breathing. In clinical studies BREZTRI:*
Improved lung function starting within 5 minutes
Improved COPD symptoms
Reduced the number of flare-ups†
*Results may vary
†Compared to a dual bronchodilator and anti-inflammatory and bronchodilator combination
Note: BREZTRI is not used to relieve sudden breathing problems and will not replace a reliever inhaler. BREZTRI is not for the treatment of asthma.
Safety Information
Like all medicines, BREZTRI can cause side effects, although not everyone gets them.
The most common side effects of BREZTRI include:
Headache
Painful and/or frequent urination (signs of urinary tract infection)
Muscle cramps/spasms
Thrush (a fungal infection) in your mouth - you may notice sore, yellowish, raised patches in the mouth, hoarse voice, irritation of the tongue and mouth or coughing
Feeling anxious
Problems sleeping (insomnia)
Cough and/or hoarse voice
Feeling sick (nausea)
Some side effects, while not as common, can be serious and may need immediate attention. More serious side effects include:
Chest or heart problems (chest pain or unusual heartbeat)
Lung infection (signs include fever, chills, more or different mucus, cough, or trouble breathing)
Breathing reaction immediately after inhaler use (chest tightness or trouble breathing)
Allergic reaction (trouble breathing, swelling, rash, or itching).
Do not take BREZTRI if you are allergic to any of its ingredients.
If you notice any of these serious side effects, call your doctor straight away or go straight to the emergency department at your nearest hospital.
These are not all the possible side effects of BREZTRI. Ask your healthcare provider or pharmacist for more information.
View the BREZTRI Consumer Information sheet here.
Learn more about BREZTRI here
Seek urgent care if you have severe breathing problems, swelling of the face/lips/tongue, or a severe allergic reaction.
Funding Information
Yes. BREZTRI is funded for people with moderate to severe chronic obstructive pulmonary disease (COPD) that meet the funding criteria. Talk to your doctor or specialist to see if it’s right for you.
Using your BREZTRI inhaler
BREZTRI is taken twice a day, with 2 puffs in the morning and 2 puffs at night.
You need to keep taking BREZTRI every day, even if you are feeling well.
For instructions on how to use BREZTRI click here.
If a dose (2 puffs) of BREZTRI is missed, it should be taken as soon as possible and the next dose should be taken at the usual time. Do not take more than one dose to make up for a forgotten dose. Contact your doctor or specialist if you have any concerns.
No. BREZTRI is not for sudden symptoms. Use your reliever inhaler as directed by your doctor or specialist. If you do not have one, contact your doctor.
Still have questions?
Talk to your GP, nurse, or pharmacist. For medicine-specific questions or to report an adverse event (side effects) or product complaint, please contact AstraZeneca NZ Medical Information: Telephone 0800 684 432 or (09) 306 5650 or via https://contactazmedical.astrazeneca.com
USEFUL LINKS:
Do not take BREZTRI AEROSPHERE® if you are allergic to any of its ingredients.
BREZTRI AEROSPHERE® is funded for COPD patients only – restrictions apply. Normal doctor’s charges and pharmacy fees apply.
For full consumer information please refer to the manufacturer’s Consumer Medicine Information available at www.medsafe.govt.nz
BREZTRI AEROSPHERE® is a registered trademark of the AstraZeneca group of companies. Registered user AstraZeneca Limited, PO Box 87453, Meadowbank, Auckland 1742. For Medical Information enquiries or to report an adverse event or product quality complaint: Telephone 0800 684 432 or (09) 306 5650 or via https://contactazmedical.astrazeneca.com TAPS MR12794 NZ-2988, Date prepared: February 2026.